Sentence examples for based on targeting of from inspiring English sources
Our observations have potential implications for future therapeutic strategies based on targeting of cell cycle deregulation such as via cyclin-dependent kinase (CDK) inhibition.
The proposed technique was based on targeting of α v β3, a key integrin protein of placental angiogenesis.
It could be expected that an efficient therapy based on targeting of HER2 would tend to induce a selection for cells with low or no HER2 expression.
Although we cannot totally rule out that this partially results from virus-host and host-host interactome incompleteness, it is also highly suggestive of viral strategy based on targeting of poorly connected proteins within the human interactome.
Our approach is based on targeting of a quenched fluorescent pHLIP-FIRE construct to acidic tumors and activation of the fluorescence by translocating the cargo dye into cells, where the reducing power of the cytosol triggers the enhanced fluorescence.
Importantly, these traits molecular mechanisms aside are essential characteristics of all life-threatening cancers, and therapies based on targeting of these characteristics molecularly are therefore broadly applicable to most if not all cancers.
The remainder of the paper presents the results of these simulations and evaluate different vaccination policies based on targeting some of these group types.
Currently, adjuvant endocrine therapies are primarily based on targeting expression of hormone receptors (Goldhirsch et al, 2007).
This novel finding provides support for alternative therapies for the treatment of DN based on targeting the regulation of the ER stress response.
The view presented has important implications for the development of new therapeutic strategies based on targeting specific elements of alanine-glyoxylate aminotransferase homeostasis.
The k-clique method in the SubpathwayMiner software was used to mine LAPs based on targets of differentially expressed miRNA as well as mRNA expression data [ 28, 29].
