Sentence examples for based on targeting hypoxic from inspiring English sources
Rational design of therapeutic strategies to overcome metastatic disease based on targeting hypoxic tumour cells and/or inhibiting the hypoxia-induced proteins that influence tumour metastasis holds great promise for improving the treatment of metastatic cancer.
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Finally, the effect of therapies that focus on hypoxia, either through improvement of tumor oxygenation, or by targeting hypoxic tumor cells should be the subject of future studies.
These prodrugs were designed as potential candidates in more selective chemotherapy by targeting hypoxic tumour tissue.
Targeting hypoxic tumour cells to reduce metastatic disease represents an important advance in the way scientists and clinicians view the influence of tumour hypoxia on therapeutic outcome.
Although the effect of TH-302 on tumour metastases has not yet been reported, TH-302 remains a promising therapeutic for targeting hypoxic tumour cells.
25 Reversing hypoxic-mediated adaptation to cell death signals may also be a critical in targeting hypoxic tumors.
As a first attempt to categorize tumours based on their hypoxic profile, three different hypoxia patterns are described.
Multiple studies using nutrient loads to predict the previous hypoxic area estimates have suggested the Gulf is becoming increasingly susceptible to hypoxia, based on increasing hypoxic area relative to nutrient loading.
