Sentence examples for based on targeting endogenous from inspiring English sources
Therapies based on targeting endogenous enteroendocrine cells, however, could potentially offer the benefits of releasing more than one peptide, thus activating appetite suppressants as well as insulinotropic pathways.
Regulus Therapeutics is a San Diego based company with a wide-range program focusing on targeting endogenous miRNAs through inhibitory oligonucleotides in hepatocellular carcinoma, kidney fibrosis, atherosclerosis, HCV infection and glioblastoma.
A technique based on light to target endogenous particles is already being exploited to treat pigmented cells in dermatology and ophthalmology.
Durant, F. et al. Long-term, stochastic editing of regenerative anatomy via targeting endogenous bioelectric gradients.
These results, which are based on ectopic targeting experiments, are likely relevant in the context of the endogenous locus.
A reporter based on an endogenous β-catenin target gene can in that case truthfully report increased activity of the pathway, but reduction is not necessarily detected as other pathways could maintain its expression.
We had previously synthesized a series of compounds based on endogenous cannabinoid ligands that targeted both CB receptors and T-type calcium channels.
Third, if participants had made eye movements to the expected target location based on an invalid endogenous cue, and subsequently had to make an eye movement toward the actual target location, it would follow that the RT difference between valid and invalid trials would be roughly 200 250 ms, reflecting the time it would take to make an eye movement.
To analyze these features we have engineered a set of model IMPs based on endogenous E. coli IMPs known to follow distinct targeting and insertion pathways.
Taken together, he said, this suggested that he had successfully imaged cerebral activation based on endogenous contrast.
