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However, the declaration-based surveillance system based on suspected cases may have also underestimated the attack rate at the epidemic phase.
The main objective of this study was to evaluate the biopsy accuracy based on suspected cases of SS referred to LSGB.
In La Réunion, the epidemic pattern was monitored through a regional surveillance-system managed by the Cellule Interrégionale d'Epidémiologie (CIRE) based on "suspected cases", defined as subjects with a sudden fever (T > 38.5°C) and incapacitating arthralgia [ 10, 11].
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On each disease, information is collected on suspected cases, laboratory confirmed cases, and deaths.
Consider a retrospectively collected matched case-control data where each case is matched to one or more controls based on suspected confounders as matching factors.
Two approaches were used to estimate malaria incidence, based on confirmed and suspected cases of malaria (the latter diagnosed by clinical signs and symptoms).
Some authorities considered them subspecies based on morphological similarities and suspected cases of hybridization.
By May 2013, a total of 8730 bovine and ovicaprine herds in 22 European countries, including Italy, were reported as being SBV-positive based on laboratory confirmation of suspected cases [ 7].
In the presence of a laboratory-confirmed epidemic, all suspected cases based on clinical criteria are considered confirmed cases.
An automated clinical decision support system to detect suspected cases, based on the principle of syndromic surveillance, is being developed at the University of Lyon's Hôpital de la Croix-Rousse.
All children aged < 2 years and admitted to the study hospitals with a diagnosis of IS categorized as definite (ascertained by: radiograph, surgery or by post-mortem examination), probable, possible or suspected cases based on the criteria developed by the Brighton Collaboration Working Group (version dated January 30 , 2002 [ 21], were enrolled.
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