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The comparison of survival outcomes based on subtypes of NHL demonstrated that MCL did not show a survival curve plateau.
Kaplan Meier plots of OS in years based on subtypes are shown in Figs. 2, 3 and 4.> Currently, decisions on adjuvant systemic treatment of breast cancer patients are based mainly on histopathological criteria including tumor size, nodal status, grading, ER, PR, and HER-2 status.
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Allele-specific PCR based on subtype consensus sequences is a powerful technique for detecting low frequency drug resistant mutants in HIV-1 infected patients.
Furthermore, the selected topics highlight the relevance of concepts derived from experimental studies for understanding GABAA receptor alterations in disease states and for designing improved therapeutic strategies based on subtype-selective drugs.
The vaccine cassette was designed based on subtype B-specific consensus sequence with several modifications, including codon optimization, RNA optimization, the addition of a Kozak sequence, and a substituted immunoglobulin E leader sequence.
Currently, the overwhelming majority of data on HIV-1 is based on subtype B, the predominant subtype in developed countries.
Most of the current knowledge of HIV-1 central nervous system (CNS) infection is based on subtype B. However, subtypes other than subtype B account for the majority of global HIV-1 infections.
The plots show that the tumors segregate well based on subtype.
Today, ~70% of patients receive adjuvant therapy, and decisions are increasingly made based on subtype classification.
This unsupervised clustering algorithm did not clearly distinguish the tumours based on subtype or histologic grade.
Briefly, the intrinsic subtypes, the risk of relapse based on subtype (PAM50-RORS), the ROR based on subtype and proliferation (PAM50-RORP) and the proliferation index (PAM50-PROLIF) were identified using the PAM50 subtype assay [ 10].
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