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But the report said that was based on "substantial and almost entirely unspecified spending cuts and tax increases" and could involve "further real cuts to unprotected departments of around £30 billion".
The decision to do this, rather than conduct an initial 'stand-alone' Phase II trial, was based on substantial and reassuring safety experience with LCZ696 in hypertension and prior experience with omapatrilat.
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The aim of this study was to identify key farm and field characteristics that drive farmers' land allocation, based on substantial datasets, and to benchmark findings for farmer perceptions with interviews.
But he defended his report, which he said was preliminary yet based on substantial fieldwork and analysis, as a contribution to "the discussion of modern human variations that has been missing in the Flores debate".
In those discussions, it became apparent that ERA steps 1 and 5 as described by Hill are not restricted to the application of scientific methodology but must also be based on substantial normative and thus value-loaded decisions [37].
Predicting the course of a future pandemic which will be caused by a virus with unknown characteristics is based on substantial uncertainties and we must rely on sensitivity analyses, performed with mathematical models like InfluSim.
The possible mechanisms for self-healing phenomenon in cementitious materials, which are summarized based on substantial experimental studies and practical experience, are reviewed.
The rates were based on substantial numbers of cases and deaths and represent cancers with relatively good (breast), moderate (colorectal) and poor (lung) prognoses.
However, most of these methods are based on substantial post-PCR processing, and for one or very few SNPs for one pooling sample as a time.
B. hinzii and B. pseudohinzii are distinguishable based on substantial divergence in sequence and gene content, as well as the presence of a CRISPR-Cas system that is unique to the genome of B. pseudohinzii.
Our reconstructions were based on substantial mtDNA (4 kb) and nuclear intron (4 loci, 3 kb total) sequences from 16 species, augmented by mtDNA NDII gene sequences (1 kb) for the remaining 10 taxa for which DNAs were available only from museum skin samples.
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