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Although the distribution of d s computed based on structure predictions by mfold is similar to the one based on RNAsubopt predictions, the average distances for RNAsubopt predictions are not as distinct between 'S' and 'L' mutants as ones based on mfold predictions.
Nevertheless, the secondary structure arrangements were similar among these ω-3 desaturases, based on structure predictions.
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Based on structure prediction algorithms it was suggested that Noc-domains and large parts of Noc-proteins fold in alpha helical repeats similar as seen in HEAT (Huntington-elongation-A_-subunit-TOR) repeat proteins [27].
Our arguments about Anbu are based on structure prediction, but a crystal structure could experimentally verify those predictions.
The effects we described were recorded in parts of the visual areas strongly connected through the CC and were strikingly consistent with the predictions based on structure of CC axons.
TMBpro is based on secondary structure predictions and prediction of residue contacts in potential transmembrane β-barrels.
Before the availability of prediction methods based on structure, peptides were selected from protein sequences using propensity scale indexes and were successfully used to raise antisera or monoclonal antibodies.
We use a machine learning-based predictor DISOPRED2, residue propensity-based IUPred and a recent DISOclust that is based on tertiary structure predictions (i.e. prediction based on the sequence-derived tertiary structure).
The region that comprised amino acid residues 112 121 was built as an α-helix of 3 turns based on secondary structure predictions using the prediction program Jpred [ 33].
Based on domain structure predictions, one of these sequences was found to encode a protein that contained two transmembrane domains and, therefore, may be a transmembrane protein.
The sequence alignment of N. salina AtpD was completed using ClustalX [ 44] and gaps were removed manually based on secondary structure predictions for N. salina protein sequences using psipred and the secondary structure observed in E coli AtpD and bovine OSCP structures.
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