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It is important to note however that the H4K16 residue is directly implicated in higher-order chromatin structure based on structural studies (Dorigo et al. 2003; Shogren-Knaak et al. 2006; Shogren-Knaak and Peterson 2006).
This control mechanism was first suggested based on structural studies of the membrane proximal D1 domain of RPTP α.
A "Rock and Lock" model has been proposed based on structural studies of pyruvate kinase from L. Mexicana (Morgan et al., 2010).
Based on structural studies, yeast ESCRT-I adopts an elongated conformation that predicts its elution volume on the gel filtration column [20].
Speculations on why KIF1A dimers show long run lengths based on structural studies on monomers are highly hypothetical.
Based on structural studies, CYTZ and TCMZ bind to two symmetrical positions along the LBD interface resulting in a stoichiometry of 2 modulator/dimer.
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The dorsal extrastriate cortex in the occipital lobe (V3A) and middle temporal cortex were reported to be relevant neural substrate for MA and MO based on structural MRI studies.
Based on structural homology studies with the c-MYB protein, we choose to replace a positively charged arginine in position 69 from the native protein (VvMYB5bR) by a neutral leucine (VvMYB5bL).
Here, we report another distinct oligomeric form of FliD based on structural and biochemical studies.
Based on structural and functional studies on PknE and PknD dimer, we mutated analogous conserved dimer interface residue His78 in PknJ-KD to Ala [41], [42].
Based on structural and kinetic studies, a postulated catalytic mechanism with the intermediates has been proposed for cystalysin [ 38, 39] and Streptococcus anginosus βC-S lyase (Lcd) [ 40], the enzymes with the highest sequence identity to C. diphtheriae C-S lyase) among structurally and enzymatically characterized βC-S lyases.
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based on structural changes
based on recent studies
based on structural arguments
based on structural linguistics
based on independent studies
based on observational studies
based on phylogenetic studies
based on epidemiological studies
based on prospective studies
based on structural sensors
based on neuroimaging studies
based on solid studies
based on preliminary studies
based on structural trends
based on structural observations
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