Sentence examples for based on structural genomics from inspiring English sources

A limited number of studies have used GWAS [ 23- 25], function clustering algorithms [ 26- 29], or machine learning methods based on structural genomics knowledge bases [ 30] to identify candidate genes for rheumatoid arthritis.

Comparative genomics analyses of microbial carotenoid biosynthetic proteins indicate a much greater taxonomic diversity then that identified based on structural and biosynthetic data, and divides microbial carotenoid biosynthesis into several, well-supported phylogenetic lineages not evident previously.

(B ) Cross-linking strategy based on structural models.

To further investigate FindMiRNA predictions we proceeded with two additional parallel analyses, the former based on comparative genomics (see later), and the latter on distinctive sequence and structural features of the hairpins.

Candidate genes were selected based on comparative genomics and gene expression analysis, which we evaluated with association and linkage mapping.

Therefore, reverse genetic approaches based on functional genomics might be quite useful.

Despite this drawback, several regulon databases are available that are based on comparative genomics methods and lack experimental evidence.

The analysis below (Table 2, and references therein) is hence mainly based on comparative genomics predictions that await experimental validations.

We carried out a novel bioinformatics screen for other possible dual-frame translated sequences, based on comparative genomics.

We analysed the structural environment of 64 CS based on existing structural data.

Microarray hybridisation and data acquisition were carried out by ARK-Genomics (Roslin Institute, University of Edinburgh) using 23 K Affymetrix GeneChip Porcine Genome Arrays based on established ARK-Genomics protocols (http://www.ark-genomics.org/protocols).org/protocols