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With a focus on small molecules, it contains names, chemical structures, synonyms, database cross-references, links to relevant literature, and classifications based on structural features and biological activity.
All purely morphological systems (i.e., classification schemes based on structural features) are artificial.
For example, a clustering based on structural features which aligns with an annotated property indicates the presence of a connection between the used structural features and the property.
Another way is to create a hierarchy based on structural features of the molecules, i.e. molecules sharing common structural features on given level are clustered together.
Nakamura et al. (1987) first advocated a recent jump of the Euler pole of the Philippine Sea plate based on structural features near the subduction zone around eastern SWJ.
Novel azo polymers were prepared for colonic drug delivery with a release mechanism based on structural features of azo derivatives designed for rapid bacterial degradation leading to soluble polymers.
Similar(26)
Consequently, DSRM-containing proteins bind RNA based essentially on structural features and not on primary sequences although, in some cases, a specific primary sequence can influence binding by inducing a particular RNA secondary structure [ 6, 7].
An objective classification system, based solely on structural features (palpebral fissure, philtrum and vermillion border) and growth deficiency (head size and height and/or weight) consistent with the revised Institute of Medicine criteria (Hoyme et al., 2005), was used to classify subjects.
The major limitation of traditional methods that are based on structural or sequential features is that they only focus on the local variation of the protein itself.
Based on structural and functional analysis, features shared by the Malyshevo, Kondon, and Voznesenskoye ceramic traditions are revealed.
In this database both peptidases and their inhibitors are classified into clans based on structural similarity or sequence features.
More suggestions(15)
based on structural techniques
based on numerous features
based on structural models
based on structural mechanics
based on reproductive features
based on structural changes
based on structural arguments
based on structural linguistics
based on specific features
based on behavioral features
based on biometric features
based on structural sensors
based on sonographic features
based on structural trends
based on structural observations
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