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"All this falls under the big umbrella of targeted drug design based on structural biology," Dr. Fauci said.
In particular, computational modeling and virtual screening of small molecule libraries based on structural biology have accelerated the identification of substrates and drug candidates of transporters.
The approach employed here based on structural biology does not lend itself easily to evaluation using statistical metrics.
A hypothesis of adaptive change that is based on the use of KA/KSvalues can be strengthened by joining the molecular evolutionary analysis to an analysis based on structural biology [ 62, 63].
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As a tool for developing new methods for determining secondary structure based on different structural biology techniques such as circular dichroism, Raman and infrared spectroscopies.
The optimization principle is based on structural risk minimization (SRM).
The SVM is based on structural risk minimization theory [46].
SVM algorithms are based on structural risk minimization.
While Incremental SVM is based on structural risk minimization.
We generated isolated CXXC domain and deletion constructs based on structural homology models to minimize structural alterations.
(B ) Cross-linking strategy based on structural models.
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