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The heterogeneity beneath the Kii Peninsula is based on structural analyses, and it acts as the segment boundary between the Nankai and Tokai earthquakes in numerical simulations (Kodaira et al. 2006).
The mechanisms involved in their polymerisation activity have been elucidated based on structural analyses of the DNA polymerase of bacteriophage RB69 crystallized under different conformations, i.e. the enzyme alone or in complex with DNA and with both DNA and incoming nucleotide.
Previous work has shown that these sets can include non-obvious groups of reactions and differ from groupings of reactions based on structural analyses of network topology [ 53, 54].
Based on structural analyses of PYR1 (Nishimura et al., 2009) and the PYL1-ABA-ABI1 complex (Miyazono et al., 2009) and a FRET cassette consisting of the fluorescent proteins mTurquoise (Goedhart et al., 2010) and Venus circularly permutated at amino acid 173 (cpVeNagai3; Nagai et al., 2004; Piljić et al., 2011), FRET-based reporters for ABA, named ABAleons, were designed.
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The 56 putative BcWRKY proteins were divided into three groups based on structural and phylogenetic analyses.
Two complementary types of neuroimaging evidence were brought into play, cortical activation measured by functional MRI and correlational voxel-based lesion/behaviour analyses based on structural MRI.
Results are compared with reported analyses based on structural data and ligand-protein contact point computations based on Protein Data Bank records.
Based on structural comparison and functional complementation analyses, the active sites of SAICARs and AIRc were identified, including a putative substrate CO2-binding site.
Network analyses based on structural equation modelling of immediate-early gene data.
In order to look for other possible miRNA candidates, additional analyses based on structural and sequence criteria were carried out as the second strategy to isolate genomic regions possibly containing miRNA precursors.
The paper by Tahirov and colleagues reports a very exciting observation: they have shown convincingly, using a combination of in silico approaches based on structural comparison and iterative Psi-BLAST analyses, that the C terminal domain of the eukaryotic DNA polymerase ε, corresponds to an inactivated DNA polymerase of the B family.
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