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In conclusion, we have presented a new compound suitable to effectively immobilize the influenza virus on streptavidin-coated surfaces based on strong binding to the influenza NA.
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These results indicated that stronger PI3K inhibition by FK-A11 is based on stronger binding to the ATP-binding pocket of PI3K.
The Norwegians adopted a cautious approach based on strong defence.
For instance, the cellular protein TRBP was originally identified based on its strong binding affinity for the HIV-1 TAR element [36] and TRBP plays a role in RNAi as a binding partner for Dicer and in recruiting Argonaute proteins to RISC [37], [38].
Based on the strong binding interaction between Hg2+ and the sulfur-containing amino acid cysteine (Cys), and the competition between Cys and a oligonucleotide for Hg2+, the proposed Hg2+-sensing system can be further exploited as a Cys-sensing method.
Tveit et al. [ 24] assumed that complexes were formed between TiF4 and hydroxyapatite, based on a strong binding of the titanium compound and the oxygen atom of the phosphate group.
The incorporation of RNAs onto HDz-NCs is based on the strong, selective binding of DPA/Zn toward diphosphate groups of the RNA backbone.
Based on the strong receptor-binding activity of bisphenol AF for ERβ (IC50 = 18.9 nM; Table 1), we expected that bisphenol AF would also have a high receptor activation potency for ERβ.
This sensor is based on the strong and specific binding of Hg2+ by two DNA thymine bases (T Hg2+ T).
In principle, since this experiment is based on affinity selection, stronger binding to bait proteins should correspond to a higher probability of detection.
The second method (i.e., peptide functionalization) is based on the binding of RC to PSiMc by strong physical attachment through a hydrophobic peptide layer (SPGLSLVSHMQT).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com