Sentence examples for based on spike in from inspiring English sources

In summary, we present an accurate description and characterization of a normalization procedure of a low-density microarray based on spike in external controls that has the potential of a broad applicability to different types of arrays including those in which there is an asymmetric distribution of the up/down-regulated genes.

CTC counts obtained from CellSearch® or CTC-Chip platforms were divided by mean CTC count (based on spike-in count calculation) to determine percent CTC recovery, for additional detail see Figure S3.

We describe a normalization/validation procedure of a low-density array (test-array) based on spike-in controls (spike RNA).

It has been argued that comparisons based on spike-in data do not necessarily translate to data derived from real biological specimens [ 22].

The loess normalization based on spike-in controls corrects the whole set of expression data constructing a loess curve on spikes log-ratios.

Raw data for each slide were normalized based on spike-in control gene CAB, and normalized data were analyzed using GeneSpring GX 10.0 (Agilent Technologies, Santa Clara, CA, USA).

In this study, we demonstrate that a composite loess normalization [ 13, 14] based on spike-in controls is the proper way to deal with low-density microarray platforms that applies also to extreme distribution of the data when the global normalization approaches will generate erroneous results.

Statistical analysis was done, using the software R [ 74] involving data normalization based on spike-ins and detection of differential gene expression.

Accordingly, researchers have begun using Wikipedia to forecast outbreaks based on spikes in searches for a particular disease, LiveScience reports.

Both the ozone and short-term particle pollution rankings are based on spikes in their daily measurements and were calculated using weighted averages; each level of the Air Quality index was given a numerical weight, and these values were then multiplied by the number of days each metro reached them.

Another approach to validate recovery and accuracy is based on spike preparations of analyte and vehicle in the diluent.