Sentence examples for based on specific mutations from inspiring English sources

"This really is going to be one of the models of how do you do personalized medicine, using the science, using the genetics to develop drugs based on specific mutations in genes," he says.

We speculate about the possibility to create tailored therapy based on specific mutations in ovarian cancer and to personalize prevention.

These observations have now spawned the so-called "basket" trials, clinical trials that enroll patients based on specific mutations rather than tumor types (e.g. NCT02201212, clinicaltrials.gov).gov

In subgroups based on specific mutation type, the RR was 66% among 106 patients with common mutations (exon deletion 19 or exon 21 L858R) and 39% among 23 patients with other mutations.

However, this is the first analysis that attempts to define the actual risk of desmoid tumors based on specific APC gene mutations while adjusting for the frequency distribution of APC mutations in an FAP reference population, in an attempt to obviate bias toward more common mutations.

This seems to lead one in a different direction than much of the current PD research based on specific single gene mutations.

The model by Vos et al. [ 17] is less well defined than the Vogelstein model for colorectal cancer, because the latter is based on specific tumour stages and gene mutations.

For phase II trials in common malignancies with many potential driving mutations, either: a. Select patients based on specific molecular characteristics, or b.

Recently, Murphy et al. (9) proposed a classification scheme for monogenic diabetes resulting from mutations that cause β-cell dysfunction, a scheme that is based on specific genetic diagnoses and points to specific therapeutic interventions.

Are these based on specific styles or buildings?

aCalculated based on Specific Gravity of 1.253.