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Our GO based quantitative modeling of GV stage oocyte was based on specific hypothesis framed in GO biological process (GOBP) terms defining the phenotype of oocyte competence and maturation.
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Specifically, examples where transgenic models were integrated into the testing program based on specific hypotheses dealing with genetic alterations in cancer genes and reporter genes will be discussed.
The above reported candidate gene association studies are based on specific hypotheses.
Early studies based on specific hypotheses identified cyclin D1, c-jun and mkp1 (MAP kinase phosphatase 1), among others, as genes upregulated after NGF withdrawal.
Each power analysis must be based on one specific hypothesis using a pre-planned data analysis method.
With approximately 850 agents currently in development for cancer treatment, it is evident that combination development must be prioritised, as based on a specific hypothesis, as well as a projected development path for the involved combination.
We have chosen each subgroup based on a specific hypothesis.
This analysis was not based on any specific hypothesis, and the results are based on relatively small numbers of tumors and likely are subject to the same reporting bias as those originally reported by Elashoff et al. (3).
The possible neuroendocrine origins of fibromyalgia have been extensively investigated, based on the specific hypothesis that abnormalities of various endocrine axes, and certain neurotransmitters, might be responsible for the development of the fibromyalgia syndrome [ 6- 8].
Based on this, the specific hypothesis that both groups would have overall illness perception significantly closer to the cutoff point was not supported.
Planned comparisons are based on testing a specific hypothesis that centers around a defined set of gene families and rests on known, validated outcomes from prior work, in this case involving both in vivo and in vitro demonstrations of oxidative stress from the organophosphates.
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CEO of Professional Science Editing for Scientists @ prosciediting.com