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But Winette van der Graaf, professor of personalised oncology at the Institute of Cancer Research, said that making decisions based on smaller studies looking at benefits other than overall survival, were important in making sure new treatments were swiftly made available to patients.
Critics of that study, however, have said that it relies on unreliable data and pointed out that it's based on smaller studies that use varying definitions of the term "trafficking".
Recently reported clinical trials of telemonitoring have not demonstrated the positive impact on hospital admissions found from a systematic review based on smaller studies.
6 19 Current information in resource-poor regions is based on smaller studies and dependent on statistical modelling rather than source data.
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Benefit was seen in studies with low risk of bias but this was based on a small number of studies.
Furthermore, most of the former analyses were based on smaller study samples [ 15, 17, 18].
MANY of the claims for other estrogens are based on small studies, some without control groups.
"It's an early study and it's difficult to make large-scale predictions based on small studies," said Ajan Reginald, the founder of Celixir, the company that produces the treatment.
Most knowledge on the occurrence of seizures in the emergency department (ED) setting is based on small studies, with only two samples of more than 1,000 patients published, these having limited generalizability [12, 20].
Most of the early literature on rib fracture was based on small studies of patients in hospital or institutions.
34 The evidence for the efficacy of these treatments is poor and is based on small studies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com