Sentence examples for based on small trials from inspiring English sources

Analysts said the vote reaffirmed that cancer drugs could win approval based on small trials that show the drug shrinks tumors.

So when a company develops a drug for patients with life-threatening diseases and no other options, the agency sometimes approves the medicines based on small trials, without a control group for comparison.

However, particular caution is needed about making negative conclusions based on small trials.

In the meta-analysis, pooled RRs were mainly based on small trials that showed a large effect or trials in institutionalised persons.

Roche Holding, the Swiss pharmaceuticals group, obtained F.D.A. approval for Xeloda, its breast cancer drug, in 1998 based on one small trial in patients who had failed to respond to two other drugs.

Moxibustion was not effective compared with sham moxibustion but it was based on one small trial.

The Cochrane review of pre-conception care for diabetic women [ 37] reported evidence of benefit was equivocal, based on one small trial with 53 women, and recommended need for further large trials.

Current practice is based on small clinical trials and physiologic data from clinical and preclinical studies.

There has been little research into extravasation due to ethical considerations limiting controlled research; most evidences are based on small, uncontrolled trials or case reports.

This finding troubles Professor Rosén as it is at odds with the results of large observational studies and is based on small randomized trials that were not designed to show a change in the incidence of death or indeed cardiovascular events.

Under another, the agency could approve drugs to treat rare, life-threatening infections based on smaller clinical trials.