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One limitation in Pcons.net is that it is based on single template models, while it is well accepted that the use of multiple templates readily can improve the quality of models (Larsson et al., 2008).
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Based on single-template approach, 20 different models were generated and the model having the lowest DOPE score is selected for model refinement and validation.
The corrections comprise: component-based normalisation, template-based attenuation correction, variance-reduced random correction, scatter correction based on Single Scatter Simulation, dead time/pile up correction, decay correction and system calibration.
It has been proposed that comparative modelling using multiple templates would produce more accurate models compared to the models based on a single template [32, 33] provided that the templates have similar levels of sequence identity with the target sequence.
In particular, a model based on a single template would be highly similar to the chosen template and may not be the best representation of the target structure.
From there, users can upload their own set of canned analyses through a web-based form, or by submitting a tabular text file, where each line in the file contains information about a single canned analysis based on a template.
The small screen, too; a TV series of the same name was one of many based on the template.
Based on the template of a sequence-nonspecific nucleic acid-hydrolyzing, single domain antibody of the light chain variable domain, 3D8 VL, we generated a synthetic library on the yeast surface by randomizing putative nucleic acid interacting residues.
As Nguyen's template (Nguyen 2009) is based on Gomaa's template (Gomaa 2004), we chose the template from Gomaa.
Top line represents the PAG template created by MRIcron based on mni_icbm152_gm_tal_nlin_asym_09a template.
Create a new document based on default template.
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