Another work has studied variable selection for the case n << p, based on single response PLS. 5 This paper considered the case p >> n (as it is common for omics-type of data), to select features from each response of a multivariate PLS.
In our analysis, we found that the elastic net regressions based on single drug responses were not successful, while drug pair data provided statistically significant predictions.
Furthermore, theoretical studies have demonstrated that coding strategies based on the responses of a population of neurons encode more information than coding strategies based on single-cell responses (Zohary et al., 1994; Abbott and Dayan, 1999; Pouget et al., 2000; Sompolinsky et al., 2001).
We were able to make isochrones for the onset of responses based on single sweep optical recordings.
Having established the primary driver of cell response at the individual cell level, this information can be used to construct a complete model of cell-nanoparticle interaction with an ab initio description of the population response based on single cell studies.
As our analyses are based on single trials, the effect on questionnaire response of using offers of charity donations, sending reminders to trial sites and when a questionnaire is sent, may need further evaluation.
We were also interested to see whether any differences between the stimuli could be discerned from the single-trial evoked response, as based on single neuron recordings in the primate, orientation selectivity seems to be developed within the first 150 ms [Celebrini et al., 1993; Muller et al., 2001].
Previous studies have tested the performance of simple decoders based on single-unit cell responses to acoustical stimuli (Fitzpatrick et al., 1997; Hancock and Delgutte, 2004; Stecker et al., 2005; Devore et al., 2009; Miller and Recanzone, 2009; Lesica et al., 2010; Lüling et al., 2011).
This time response was measured using the same method as that used for the photodetector based on single CdTe NWs.
A response surface methodology (RSM) was used to optimize the parameters on UAE based on single factor experiment.
