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An optical imager is reported based on single photon avalanche diodes.
For voxelized primitives, a new sampling technique called the fractional photon emission technique is introduced to reduce sampling computations for existing techniques based on single photon emission.
The latter is based on single photon counting and is made by an objective lens Plan10x (Nikon, Tokyo, Japan) to collect light and to couple it into a multimode optical fibre (OF), connected to the multispectral detector (Multi-PMT).
A study based on single photon emission computed tomography also suggested a functional impact of cerebellar lesions on cortical functioning through disruption of cerebellar-cerebral connections, indicating a role of the cerebellum in emotional processing [ 50].
Further studies using imaging genetic approaches based on single photon emission computerized tomography (SPECT) or positron emission tomography (PET) will be required to investigate NE gene effects on regional cerebral perfusion or metabolism in ADHD and to evaluate the association of SLC6A2 genetic variation with levels of NE activity in the brain.
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The emergence of a new type of imager based on single-photon avalanche diode (SPAD) arrays built on CMOS technology [ 12, 13] is enabling high parallelization of TCSPC acquisition in a compact and cost effective manner.
The microcavity layout could be integrated in a lab-on-a-microchip design for ultrasensitive microfluidic analytics and can be considered as an important improvement for single photon sources based on single molecules operating at room temperature.
However, based on single scattering theory, we can obtain the probabilities for a photon's trajectory and calculate its multiple scattering arrival probability at the detector.
Here, we propose an innovative detection system based on a Single Photon Avalanche Diode (SPAD) with high sensitivity and low noise, crucial features for an efficient chemiluminescence biosensor.
3D-RD RBM dosimetry was based on the lumbar vertebrae, delineated on single photon emission computed tomography (SPECT) scans acquired directly, 3, 24, and 72 h after 177Lu administration.
(e) Discriminability index (Δm; see Supplementary Note 2) based on all single-photon experiments (circle with error bar) and fit to the model (black diamonds).
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