Sentence examples for based on single molecule from inspiring English sources

Based on single molecule counting technology, a multiplex instrument was designed and built that is capable of detecting cytokines and other low-abundance proteins at sub-pg/ml quantities in human plasma samples.

In this letter, a theoretical scheme based on single molecule force spectroscopy experiments and related theories, has been followed to capture the effect of the change of pH for a slow protonation-coupled folding unfolding process, and the free energy landscape has been quantified in terms of protonation numbers, barrier height and pH, following Kramer's barrier crossing formalism.

Furthermore, an independent research group has described a new approach based on single molecule DNA sequencing of cell-free DNA in maternal plasma [ 96].

The role of TATA bubbles and their lifetimes has been further discussed using a stochastic model of dynamics based on single molecule experiments [ 19, 20].

Therefore, new sequencing technologies based on single molecule sequencing might offer further opportunities to eventually obtain a genome build and SNP chip that in actuality covers the vast majority of the chicken genome.

The Erenna Immunoassay System (Singulex) is based on single molecule counting technology [ 16] and typically allows a 20-fold to 100-fold increase in sensitivity compared with traditional detection systems.

The microcavity layout could be integrated in a lab-on-a-microchip design for ultrasensitive microfluidic analytics and can be considered as an important improvement for single photon sources based on single molecules operating at room temperature.

A number of phylogenetic studies based on single molecules have suggested a more basal position of Acoela and Nemertodermatida [5] [11], while the monophyly of the Catenulida and the Rhabditophora has been recently confirmed [33].

To overcome this limitation, several super-resolution fluorescence microscopy techniques based on single-molecule localization have been developed in recent years, such as stochastic optical reconstruction microscopy (STORM) (Rust et al., 2006), photo-activated localization microscopy (PALM) (Betzig et al., 2006) and fluorescence PALM (fPALM) (Hess et al., 2006).

The results of this work prove that the developed fabrication process is a good alternative for the fabrication of single molecule DNA biochips and it allows developing a variety of innovative bio/chemical sensors based on single-molecule DNA sequencing devices.

Alternatively, nucleosomes may undergo structural changes related to the chirally reversed nucleosome ("reversome") recently proposed based on single-molecule studies [17].