As an attempt to meet this need for more 'personalized' information to guide treatment, additional ways are being studied to classify individual tumors, based on single biomarkers or more complex molecular signatures.
For instance, ecomorphological convergence may confound morphology-based phylogenetic inferences, and previous molecular phylogenetic studies based on single genes have often yielded contradictory and poorly supported trees.
The moderately good enantioselectivity exhibited by these catalysts have been explained based on single crystal X-ray data and molecular modelling studies.
The increasing availability of DNA markers provides new metrics of inbreeding based on single nucleotide polymorphisms (SNPs), i.e. molecular inbreeding or the proportion of runs of homozygosity (ROH), as alternatives to traditional pedigree-based inbreeding coefficients.
Molecular analyses to date show no evidence to support the classification scheme developed from the R&F analyses, but most molecular studies have been based on single genes [see [ 16, 20, 26, 27]].
For comparison, morphologies of the TPUs based on single soft segments (PTMO, PHEC, PDMS and PEO) with varying molecular weights and hard segment contents were also simulated.
Developments in molecular genetic technology have now made available very dense marker maps based on single nucleotide polymorphisms, which will soon be available for sheep.
Highly disparate molecular profiles of spatially separated tumor areas within the same tumor may preclude development of molecularly targeted therapies based on single tumor biopsies.
If smallpox vaccines are not clones but rather pools of virions that vary at the molecular level, assuming relatedness based on a single molecular variation is even more difficult.
