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Remarkably, one SNP locus (CaSNP8: G/A) in the coding region of constitutive photomorphogenic9 (COP9) signalosome complex subunit 8 (CSN8) gene showing tight linkage with a major SW robust QTL (CaqSW1.1) (based on single marker analysis of traditional QTL mapping) was considered as one of the potential candidate regulating seed weight in chickpea.
Marker RM1089 was associated with number of tillers and yield per plant, RM423 with leaf senescence, RM584 with leaf width and RM229 with yield per plant, based on single marker analysis of F2 mapping population from the cross between IR64 and NH219.
However, evidence for selection based on single marker Fst values should be interpreted with caution [ 54].
QTL (Quantitative Trait Loci) analysis was carried out based on single marker and interval mapping methods.
The GeneChip Human Mapping 500K Array Set (Affymetrix, Inc., Santa Clara, CA, USA) used in the DGI GWAS has coverage in the CEU HapMap population (r≤0.8) of 67%, based on single marker test.
It has been shown that a model including both haplotypes based on multiple markers and relationships between them, yields ~25 to 500 times as many effects that need to be estimated as a model based on single marker alleles [ 3].
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Those results were based on single marker-trait associations in a genome-scan to identify broad chromosomal regions potentially containing genes affecting traits of interest.
Conventional GWAS approaches, based on single markers, require of large cohorts, typically unavailable in rare diseases.
PAMs' information (except that of the ILG motif) was used to design bipartite networks models capturing network relationships based on single markers under two different scenarios.
The test of association between a marker and QTL and the power of the test were calculated based on single-marker regression analysis.
Our previous classification of SERMs in these two cell lines was based on one single marker of E2-responsiveness in these breast cancer cells: E2 and 4OHT produced oestrogenic effects on the activation of TGFα mRNA in cell expressing wtERα whereas Ral and ICI were anti-oestrogens (Levenson et al, 1998b).
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based on single loci
based on single instruction
based on single value
based on multiple marker
based on single pore
based on single degree
based on single strand
based on vertical marker
based on single droplet
based on single training
based on single detection
based on single particle
based on single factor
based on genetic marker
based on polymorphic marker
based on conserved marker
based on single electron
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