Sentence examples for based on single copy from inspiring English sources

Data are based on single copy genes (numbers in circles indicate the number of copies found).

Currently, the main genotyping method is based on single copy microsatellite markers, which limit direct genotyping from amniotic fluids (AFs) to samples with a high parasitic load.

As the current microsatellite typing method is based on single copy targets [ 8], the use of a multicopy gene such as B1 was expected to improve the number of typable samples.

We established a rescue assay based on single copy integrants of GFP-tagged CYK-4 transgenes driven by the cyk-4 promoter inserted at a defined locus in the C. elegans genome using Mos1-mediated integration (Frøkjaer-Jensen et al., 2012).

The primers were designed on the basis of IGS sequence (Intergenic Spacer of rDNA), a multi-copy region in the genome that permits to enhance the sensitivity of the assay in comparison with PCR assays based on single-copy sequences.

Although all 13 rapidly mutating Y-STRs were already multiplexed, no single assay based on single-copy markers allowing at least a portion of close male relatives to be differentiated from one another is available.

The specific primers were designed on the basis of IGS sequences (Intergenic Spacer of rDNA), a multicopy region in the genome that permits to enhance the sensitivity of the assay in comparison with PCR assays based on single-copy sequences.

For example, P. letzii and P. europaea have identical sequences for several nuclear coding and non-coding loci and were difficult to diagnose based on single-copy RFLP markers [ 14] but formed well supported monophyletic groups for all mt loci.

Network analysis of 1,000 individuals, selected at random in the same population proportions as the full set of 7,784 samples and based on single-copy Y-STRs, displayed little geographic clustering with RM Y-STR haplotypes (Fig. 4B, perhaps with the exception of North Africans), whereas with Yfiler haplotypes for the same individuals (Fig. 4A), geographic clustering is seen with several groups.

First, we used the dating method BATWING [Wilson and Balding, 1998] to estimate the TMRCA (time to most recent common ancestor) of each set of chromosomes in the three haplogroups, using 16-locus haplotypes based on single-copy microsatellites, excluding DYS385.

In this paper, we rely on a map evolution model based on single- and double-copy duplications.