It enhances the fluorescence of malachite green (MG) dyes by a factor of more than 11,000 and thus activates MG to a similar extent as FAPs based on single-chain variable fragments.
Constructs based on single-chain variable fragments (scFv) may have favourable diffusion characteristics in solid tumours, but few descriptions of this approach have been published (Bhatia et al, 2000).
The effects of long-range connectivity between urea hard domains on the microphase morphology and mechanical properties of novel, segmented, non-chain extended polyureas based on single isocyanate molecules were analyzed.
However, our lives are not based on single issues.
All values are based on single analyses.
For a single PFS macromolecule (DP=80) operating cycle, a work output and an efficiency of 3.4×10−19 J and ∼5%, respectively, were estimated based on the single chain experimental data.
Herein, we report on a novel binding pair based on a single chain fragment variable antibody, scFv, with nanomolar affinity to a hapten, where the scFv is fused to a tumor-targeting affibody.
We developed a rapid and sensitive immunoassay for influenza H3N2 detection based on single-domain antigen-binding fragments of camelid-like heavy-chain antibodies.
The tracer is based on engineered single-chain VEGF (scVEGF), expressed with cysteine-containing fusion tag (Cys-tag) for site-specific conjugation of PEGylated bifunctional chelating agents, HBED-CC or NOTA, suitable for labeling with 68Ga at ambient temperature.
These binding proteins are based on antibody single-chain variable fragments and activate fluorogenic dyes, which only become fluorescent upon activation and do not fluoresce when free in solution.
We describe the construction of a radioligand based on a single-chain antibody specifically targeting activated platelets in an in vivo mouse model of wall-adherent non-occlusive thrombosis in the carotid artery, which imitates the surface of an inflamed or ruptured plaque.
