Although the burden of MRSA infection has not been systematically estimated nationally, past estimates have been based on single-center or selected population-based studies in the United States.
First, this study was based on single-center stroke registry data.
However, published estimates vary widely and have been based on single-center or local data with limited applicability (4, 7).
However, due to the nature of the disease, most of the studies were retrospective and the conclusions were drawn based on single-center experience.
However, these studies are often small and are based on single-center data because data collection is time-consuming and costly, and their design is often open to recall and selection bias.
However, this cut-off is based on one single center study including few patients.
Treatment recommendations are mainly based on retrospective single center series, usually covering small patients numbers treated over many years with various combinations of surgical approaches and radiation treatment modalities.
Miranda et al., based on a single center data, suggest that CSDH could be considered as a surrogate marker for underlying chronic diseases, which explains an accelerated mortality despite initial successful treatment [ 4].
Although it is difficult to generalize these findings based on a single center study to the remainder of the US medical educational institutions, our findings are consistent with reports from diverse educational settings in Europe and Asia.
The lack of knowledge of spatial variation of oxidative properties limits the use of this novel information also in the ECRHS cross-community comparisons that are based on one single monitor per center.
Over the past decade, innovations in the field of pediatric imaging have been based largely on single-center and retrospective studies, which provided limited advances for the benefit of pediatric patients.
