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The Kd values for monovalent and divalent copper, based on single binding isotherms, are 450 and 540 nM, respectively.
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As we observed significant sequence and structural similarity between the B7-binding ligand, cytotoxic T-lymphocyte associated protein-4 (CTLA-4), and antibody variable light chain domains (VLs), we have explored the possibilities of making novel B7 binding molecules based on single VL domains.
Based on single concentration measurement data from Ambit BioSciences, including estimated IC50 values for the binding of >20,000 compounds to 300 400 protein kinases, researchers at Bristol-Myers Squinhibitorated inhibitor selectivity profiles with an "activity homology" (AH) score [80] (see "Methods").
However, our lives are not based on single issues.
All values are based on single analyses.
We developed a rapid and sensitive immunoassay for influenza H3N2 detection based on single-domain antigen-binding fragments of camelid-like heavy-chain antibodies.
Based on single-channel recordings, a study published in 2003 suggested that capsaicin binding stabilizes the channels at high open probabilities (Hui et al., 2003).
Here we present a family of novel photoacoustic contrast agents that are based on the binding of small optical dyes to single-walled carbon nanotubes (SWNT-dye).
Based on the binding poses predicted by molecular docking, single-point mutations were designed to test their impact on ligand binding.
Therefore we generated human single chain and diabody antibody derivatives based on the binding characteristics of the murine monoclonal antibody Guy's 13.
In specific, optical biosensors have been developed based on the preferential binding of single stranded nucleic acid on GO and fluorescence quenching capability of GO.
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