Sentence examples for based on sequencing depth from inspiring English sources

Around half of candidate sites were predicted with high confidence based on sequencing depth.

Our goal was to gain the ability to confidently assign quantitative significance to individual insertion sites based on sequencing depth.

However, FPKM determination is not absolute and can vary significantly based on sequencing depth, sequencing platform, RNA source and other factors [ 32].

edgeR was also used to correct for sample-specific variation, normalizing the data based on sequencing depth (total read counts per sample) and RNA composition (weighted trimmed mean of log expression ratios -TMM).

Per-base coverage was calculated for each locus using coverageBed, pooled across all loci for each position relative to the TSS or TTS and normalized based on sequencing depth.

As noted above, the likelihood that a homozygous SNP in 4 of 17 murine strains represents sequence error is minimal (<1 in 10 based on sequencing depth and high Phred quality) and manual SNP assessment indicates authenticity of the homosites identified here.

Using a binning procedure, readDepth calls copy number variants based on sequence depth, and then invokes a circular binary segmentation algorithm to call segment boundaries.

Filtering options are highly flexible and include filtering based on sequence depth, alternate allele ratio, and SNP quality on top of the SWEEP filtering procedure.

Specifically, an R package named readDepth can detect CNVs based on sequence depth and then invoke a circular binary segmentation algorithm to call segment boundaries [ 47].

The readDepth uses a binning procedure to call copy number variants based on sequence depth and then call segment boundaries using a circular binary segmentation algorithm.

This lack of triplet expansion is further supported by copy number estimates of DUF1220 domains based on sequence read depth (Sudmant et al. 2010), which estimates that copy number in chimp of the HLS DUF1220 triplet-containing gene NBPF14 is a fifth of that in human.