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These data are estimated to derive from at least 1800 genomic species based on sequence relatedness, including 148 previously unknown bacterial phylotypes.
The 19 IiDIRs were clearly separated into three distinct groups based on sequence relatedness.
The separation based on sequence relatedness is matched by separation of gene functions, since all known members of the TPS-g subfamily produce acyclic products.
In order to cluster the 583 full-length LTR retrotransposons of oil palm into families based on sequence relatedness, we eliminated sequence redundancy according to the recommendations of Wicker et al. [ 1], i.e. elements are deemed related if a sequence identity of at least 80%% is detected across 80%% of the length of the retrotransposon.
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We believe our analyses provide overwhelming evidence in favor of a (USP15,(USP4,USP11)) branching pattern as opposed to the (USP11(USpattern5)) pathatn that would be inferred based on sequenced relatedness [ 19, 20].
The initial classification of Fox proteins based on sequence-relatedness within the WHD established fifteen subclasses of the Fox gene family [ 15], and four additional Fox subclasses were subsequently identified [ 16, 17].
This is consistent with the lack of relatedness of these genes as determined based on sequence analysis (refer to Figure 4).
Based on sequence differences in the DNA, they built a family tree that showed the relatedness of the various samples.
To first determine the whole-genome relatedness of phages ΦCP9O, ΦCP13O, ΦCP26F, and ΦCP34O to each other and to other Clostridial phages, we used two approaches: correlations of tetra-nucleotide frequencies and clustering of predicted proteins based on sequence similarities.
These 92 genes can be further classified into 14 gene families or subfamilies, including those encoding solute carriers, short-chain dehydrogenase/reductase, and UDP galactopyranose mutase etc (Table 1), based on their sequence relatedness 30-800% protein sequence identities and similar tree topologies) and GO annotation information (Additional file 1).
We therefore propose to group the remaining six MSP3-related proteins based on their sequence relatedness and antigenic cross-reactivity as constituting the P. falciparum MSP3 family of proteins.
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