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Each alignment algorithm was run in triplicate with randomly shuffled sequences for each run, to avoid bias based on sequence input order, and averages of these three runs are reported.
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Although the correction of sequence data are generally inappropriate for metagenomic analysis, PRICE did implement a feature that filters input data based on sequence quality scores in a user-controllable and dynamic manner.
This software not only predicts the variable sites based on input sequence data, but also groups these into co-segregating haplotypes and provides guidance as to the ways in which these may maximally discriminate genomes using the fewest possible assays.
OligoArray output, besides microarray design, provides hints on the quality (e.g. degree of redundancy) of input sequences by declaring how many specific probes can be designed based on input sequences.
A cross-correlation based on the input sequence and the downstream signal measured by the thermistor is performed.
Primers for the insertion sites of the group II intron were chosen by a Sigma-Aldrich computer algorithm based on an input sequence from the hcnBC genes.
It should be noted that the p-values computed by MEME and presented in Tables 4, 5, 6, 7 and 8 are computed based on the input sequences given, and not the entire E. coli genome.
The sequence identity between each pairwise comparison is isolated, and after every sequence in the database has been analyzed, the sequences are sorted from high to low based on the sequence identity to the input sequence.
We observed that PepSurf method groups the input peptide sequences based on their sequence identity and maps the high scoring group on to antigen surface.
The function F estimates the log-likelihood of one sequence residue being aligned to one template residue based on the input protein features.
The MM-LINC sequence is based on the input samples ("1," if the instantaneous envelope is greater than the threshold, "0" otherwise), and in our proposal, it is based on the mathematical properties of a Markov process.
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