Sentence examples for based on sequence complementation from inspiring English sources
They specifically bind mRNAs in their 3' UTRs based on sequence complementation and lead to translational repression and gene silencing [ 18].
MicroRNA (miRNA) is a class of small noncoding RNA molecules that usually lead to translational repression and gene silencing through the specifically binding 3′ untranslated region of messenger RNAs based on sequence complementation at the post-transcriptional level (6).
Two candidate genes, LOC_Os07g41180 and LOC_Os07g41200, encoding RNA-binding protein and unknown expressed protein respectively, were selected based on sequence variations and transcriptional expression and to be further testified by complementation test.
Our approach was based on sequence mining.
(2) Filtering Based on Sequence Similarity Rate.
Here, we describe the application of two such cAMP biosensors, one based on enzyme complementation and luminescence detection and another using Förster resonance energy transfer and fluorescence detection.
The potential target genes of miR-638 were analyzed using the TARGETSCAN-V ERT 6.2 [ 27] and miRanda, which help identify targets based on comparative sequence analysis, seed match complementation and Z-score for assigned untranslated regions (UTRs) and coding sequence (CDS) region.
This shuttle vector employs an antibiotic resistance-free mechanism for plasmid selection and maintenance based on glycine complementation in E. coli and lysine complementation in mycobacteria.
To overcome this limitation of Cre/LoxP-mediated DNA-recombination, we added a second dimension of recombination control by designing a novel "split-Cre" system based on the complementation of Cre protein fragments.
Re-introduction of a functional NRPD1 allele in this manner restored siR1003 production to wild-type levels, as expected based on previous complementation and out-cross experiments [5], [19].
Pairwise interactions were tested based on growth complementation on nutritional selective media.
