Sentence examples for based on sequence annotation from inspiring English sources
Database hits were curated manually based on sequence annotation and reference to the literature; initial hits caused by contamination of the RefSeq database by non-human sequences (corresponding mostly to viral or bacterial elements) were removed from further analyses.
The analysed set of 210 sequences was obtained by thorough and detailed searches of public databases: GenBank [ 128], UniProt [ 129] and TBestDB [ 130] based on sequence annotation and similarity searches made by BLAST.
Based on sequence annotation, the major differences in gene expression between the two genotypes were identified as being associated with abiotic/biotic stress tolerance (at low levels), transcription factors and signal transducers.
Thorough and detailed searches of public databases based on sequence annotation and similarity enabled us to gather as many as 210 non-redundant sequences representing Rab7 and Rab9 proteins.
In contrast to the differential protein profile generated under LB-chromate conditions, M9L proteins grouping in the role category of inorganic ion transport/metabolism were not specifically related to Fe uptake and utilization based on sequence annotation but instead had functions in the uptake of alternative sulfur sources or unknown substrates (e.g., ABC transporter related).
The different characteristics (length, repeat sequences and genes) are listed in the Additional file 5. Based on sequence annotation results, 40 ovine genes, of which 37 have not been described in sheep yet, could be mapped on the mini-contigs by comparative mapping with the bovine genome.
Annotation based on sequence similarity and annotation based on association rules between CAZy families and pfam domains against the CAZy database (http://www.cazy.org/) were integrated for CAZyme protein predictions.
Putative plant cell wall polysaccharide-degrading enzymes belonging to different CAZy families were identified and classified based on sequence-based annotation.
A suite of tools is available that allows users to search the loci based on sequence and functional annotation.
Published streptococcal and other 16S rRNA sequences were extracted from EMBL using proprietary extraction methods based on sequence profiles and annotation searches; representative sequences for each species were determined using a proprietary algorithm developed by SmartGene for bacterial 16S rRNA sequences (SmartGene IDNS™ Bacteria Module).
We classified the sequenced RNAs based on sequence comparison and genome annotations.
