Clades of cultivated and uncultivated taxa were formed based on sequence analyses using multiple criteria, including maximum-likelihood-based topology and bootstrap support, genetic distance, and previous naming.
Hence, it is difficult to reliably predict the properties of C2 domains based on sequence analyses alone, and the basis for functional differences among synaptotagmins is poorly understood.
Based on sequence analyses of multiple housekeeping genes (i.e. clpA, clpX, nifS, pepX, pyrG, recG and rplB) of the B. lusitaniae samples analyzed in this study (Table 1), 13 sequence types (STs) were defined by MLST, and no ST was observed in more than two samples (Table 2).
The three intragenic AP-1 binding sites are very well conserved at the nucleotide level as represented in Figure 2A by sequence logos that symbolize the frequency of the nucleotide present at each position in these binding sites based on sequence analyses of the full spectrum of HIV and SIV (Simian Immunodeficiency Virus) sequences compiled in the HIV compendium database (hiv-web.lanl.gov).
Based on sequence analyses, SitA is annotated in the UniProt Knowledge-Base as a putative metal-binding protein.
Based on sequence analyses of PSORT II, AtHDA5, AtHDA14, AtHDA15, and AtHDA18 contain nuclear localization signals (NLS) which follow a bipartite, pattern 7, or pattern 4 type NLS.
Based on sequence homology analyses, we identified the Kunitz-type protease inhibitor (KPI) domain of human amyloid-β A4 precursor protein as being a potential candidate.
Here, we firstly re-investigated speciation issues in the L. maculans- L. biglobosa species complex based on sequence data analyses.
As further support for their importance in the chlamydial outer membrane, several studies showed disease-correlated serum reactions for Pmp proteins [ 58, 61, 62], and there are indications for tissue tropism-related differences in the Pmp proteins based on sequence clustering analyses [ 17, 18].
Based on sequence and structural analyses, we predicted the significance of targeting human APN residues: Ala-351, Arg-442, Ala-474, Phe-896 and Asn-900 for improving the selectivity of the identified compounds.
In contrast, Hidaka-No.119/2012 did not come from an Obihiro12-1-like virus based on sequence and phylogenetic analyses.
