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Based on screens for mutant sensitivity against DNA damaging agents a large number of DNA repair and DNA damage checkpoint genes have previously been identified in genetically amenable model organisms.
Under conditions of local drift, measures of prevalence should be based on screens for infection in several demes, because strong drift can generate local variation in infection frequency.
Indeed, new aggregation prone prions have been identified based on screens for Q/N-enriched proteins and subsequently experimentally validated in the labs of Lindquist and Weissman (Alberti et al., 2009 ; Michelitsch and Weissman, 2000 ).
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Based on screening for these 11 prevalent mutations, 58% were carriers of one or more FLG mutations (42% FLG+/+; 38% FLG+/−; 20% FLG−/−).
Antiviral therapy can be guided by viral drug susceptibility testing based on screening for known resistance-inducing mutations in the viral genome.
According to two knowledgeable sources, the person in question had lost his human reliability rating, which is based on screening for drugs, alcohol abuse or mental health problems, among other things.
Our results on the presence of CD4+CD28null T cells in the synovial fluid were based on screening for CD3+CD4+CD28- cells.
The clones were quantitatively scored for susceptibility to Heterobasidion spp. based on screening for visible decay in the stand in 2004 [ 7].
Based on screening for neuroglobin expression using a mouse monoclonal anti-neuroglobin Ab (13C8) (Abcam, Cambridge, UK) three stable clonal cell lines were selected for further analysis.
Putative downstream targets of CEBPβ, E2F1, PAX6, RELA and STAT1 were identified based on screening for corresponding transcription factor binding sites within promoter regions using HMM algorithms [ 64].
The studies from South Thames UK, 3 Cambridgeshire UK, 5 Goyang City South Korea 6 and Bergen City Norway 24 were based on screening for ASD among children with special educational needs or those who were on a disability registry, and/or screening among children in elementary schools, and/or among local clinicians.
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