Sentence examples for based on scientific rationale from inspiring English sources

The juvenile toxicity study design is approached case-by-case based on scientific rationale and should mimic the pediatric clinical trial.

However, juvenile animal studies should be designed thoughtfully to fulfil a purpose based on scientific rationale, with each endpoint carefully considered in terms of practicality and interpretability of data generated.

The use of oral small molecule HER-2 kinase inhibitors in combination with conventional cytotoxics and other targeted therapies based on scientific rationale represents the future for this important class of therapeutics.

Yet the prediction of drug resistance mechanisms and design of therapeutic combinations based on scientific rationales is still an unmet need.

Decisions on how those new techniques should be regulated may not be based entirely on scientific rationale, and even if it is decided that crops produced by NBTs do not fall under the umbrella of genetically modified organisms (GMOs), their commercialization is by no means certain at this time.

The rationale for our study was based on scientific evidence demonstrating that calcitriol binds to VDRS in breast cancer cells resulting in direct and indirect inhibition of proliferation through regulation of genes encoding cyclin proteins, cyclin-dependent kinases (CDK), and CDK inhibitors and indirect promotion of differentiation, apoptosis, and angiogenesis in breast cancer cells 15, 37– 37.

In line with general guideline (II), a rationale for the selection of instruments should be provided, preferably based on scientific research and/or best practice.

But decisions must be based on scientific evidence.

Lees said the work was based on scientific research.

The decisions are supposed to be based on scientific evidence.

It was a reasonable decision, based on scientific evidence.