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This was based on rodent models in which the regenerative response of muscles was examined after an induced injury.
First, our observations are solely based on rodent models.
Nonetheless, it is noteworthy that our findings were mainly based on rodent models and in vitro experiments.
20 Studies with iBREC ideally complement investigations based on rodent models of diabetes and may even be more relevant to clinical applications of drugs under investigation, because of the higher similarity of bovine proteins to their human counterparts.
On the other hand, among the W-scoring retained candidates only 14.9% of genes was selected based on rodent models and more than half of the retained candidates (51.5%) were selected using human data (Additional file 5).
71 examined the use of the cytochrome P450 inhibitor piperonyl butoxide with the aim of prolonging the elimination half-life of bumetanide and thus increasing the translational value of results based on rodent models.
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The first set of models, exploring the glucagon counterregulation mechanism, were proposed by Farhy and McCall, (S127, S128) based on rodent studies.
Creating biologically-plausible Simultaneous Localization And Mapping (SLAM) and navigation algorithms based on rodent hippocampus and entorhinal cortex.
Much of the research examining the safety of pediatric vaccines is based on rodent data.
With regard to its experimental handling and practicability, as well as its evolutionary distance from humans, this model will help to fill the gap between pre-existing models based on rodents and macaques.
This systematic review selected 39 articles, 26 involving humans and 13 based on rodents.
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