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Based on reversion rate measurements, we also found that the mutation rate increased linearly with increasing EMS concentration (Figure 1; R2 = 0.26, F1,196 = 68.62, P<0.001, the R2 value is low due to the substantial number of populations that did not exhibit reversion).
We propose that gish is a suppressor of para bss1/+ based on reversion of phenotypes by gish /+, by ELAV-Gal4 C155-driven UAS-gishRNAi, by Df 3R ED10639/+, and by Df 3R) Exel7329/+.
The preclinical studies described herein were designed to assess whether eribulin might have such anti-metastatic properties, based on reversion of the metastasis-promoting process termed as epithelial mesenchymal transition (EMT).
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Our system is based on the reversion of a nonsense mutation in an EGFP gene, cloned downstream of the CMV promoter/enhancer.
In the current study, we sought to identify epigenetically silenced genes in MCL using an initial genome wide screening based on pharmacological reversion of CpG methylation and gene expression microarray analysis in MCL cell lines followed by the analysis of selected methylated genes in primary MCL and normal B lymphocytes.
In order to examine if AID is able to trigger mutations in the absence of DNA replication in a non-B cell line, we developed a highly sensitive assay based on the reversion of nonsense mutations of the EGFP gene cloned in a non replicating vector.
Based on this reversion experiment, it was concluded that in A6/PS11 of Fab-7 1 flies, the iab-6 and iab-7 domains are fused into a single functional unit with mixed characteristics: parasegmental/segmental address is provided by iab-6 and parasegmental/segmental identity is provided by iab-7.
Based on the series reversion method, a non-linear CS (NLCS) process was applied to equalize the azimuth chirp rate in bistatic SAR focusing for general configuration [34], and a range Doppler (RD) algorithm was proposed to handle the azimuth-invariant bistatic case [35].
This is based on a Lac+ reversion experiment done on medium containing (in addition to lactose) nutrients that cannot serve as carbon source, but would allow colony formation by Lac+ mutants that carried secondary mutations in any of ∼100 genes.
The multiphase microstructure evolution and mechanical properties of an ultra-low carbon medium manganese quenching-partitioning-tempering (QPT) steel have been investigated based on the nanoscale austenite reversion correlated with the co-precipitation behavior.
Revertants were initially identified based on eye color and reversion of the lethal insertion phenotype, then confirmed by PCR.
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