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However, one group has suggested, based on retrospective studies of small cohorts, that patients with tumours harbouring G13D mutations may benefit from therapy with anti-EGFR antibody therapy, suggesting that all codon 12 and 13 mutations may not be equal in terms of their clinical impact (De Roock et al, 2010b).
Although much of the current standard of care in veterinary oncology is based on retrospective studies or transference from the human literature, a new era of clinical trial awareness brought on by new consortia and cooperative investigative groups is beginning to change this limitation.
This belief has been based on retrospective studies relating bowel dysfunction to hysterectomy.
Therefore, therapeutic decisions are usually based on retrospective studies and case reports.
The clinical evidence for this recommendation is based on retrospective studies and case series.
For this reason, treatment decisions will need to be based on retrospective studies and institutional experiences such as presented here.
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This makes it difficult to determine the key risk factors for severe injuries based on retrospective study designs.
Findings mainly based on retrospective study designs, lack of control groups, missing randomisation and small sample sizes all lead to a weak level of evidence.
Evidence that lactation duration influences incident type 2 diabetes after GDM pregnancy is based on one retrospective study reporting a null association.
Two studies recruited patients prospectively [ 9, 10], whereas most past research is based on retrospective cohort studies.
Studies specifically designed to ascertain the role of beta-blockers in patients with COPD with cardiovascular conditions are still needed, because the majority of the current evidence is based on retrospective observational studies.
More suggestions(16)
based on earlier studies
based on retrospective questionnaires
based on retrospective measurements
based on retrospective assessments
based on recent studies
based on retrospective cohorts
based on observational studies
based on retrospective reports
based on independent studies
based on phylogenetic studies
based on prospective studies
based on epidemiological studies
based on neuroimaging studies
based on solid studies
based on preliminary studies
based on single studies
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