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Thus, most of the ARORs have intrinsic enhancer potential, although in most cases this potential is either not materialized or not detectable when the AROR is assessed in its native context based on responsiveness of adjacent genes in C4-2B cells (Figure 2 and see Discussion).
Therefore, the eradication of cancer cells in ectopic environments requires an understanding of their resistance to anchorage dependence for growth and survival based on responsiveness of their normal counterparts.
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This led the NTP (2001) to state: Because of clear species and strain differences in sensitivity, animal model selection should be based on responsiveness to endocrine-active agents of concern (i.e., responsive to positive controls), not on convenience and familiarity.
To estimate the impact of the omission of these cases, we focused on a decomposition of the 34% of cases (556/1657) who had not attrited by wave 3. Our best estimate of those we would have lost has a lower and upper estimate based on responsiveness patterns among these 34% of cases.
Based on the responsiveness of the RSDI we observed, combined with its ease of administration and applicability, this instrument should be considered for future use in other clinical studies of rhinitis and sinusitis.
Patients were also grouped by type of cancer, because some studies suggested that selectivity in the EOL chemotherapy regimen was based on the responsiveness of the cancer type.
However, based on the responsiveness of the MSTS for amputees, it should be noted that this advantage is rather a computed value than true superiority in physical functioning, and substantial differences in subjective evaluation are yet to be shown.
The incorporation of control probes within a probe set, such as X and Y linked probes and a non-human probe, allow the user to assess non-specific probe binding and adjust washing conditions as necessary, as well as confirm that any copy number changes can be detected accurately based on the responsiveness of the control probes.
These components of airway responsiveness were measured based on the response of RL to saline and increasing intravenous doses of Mch.
"We have been highly successful in this area based on our responsiveness and consistency of approach.
Based on hormonal responsiveness, the development of effective prevention strategies for breast, endometrial, and ovarian cancers is a paramount opportunity in the care of women at risk for those malignancies [ 1].
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