The PI3K-GS, derived in vitro, was based on repression or induction as a result of treatment with PI3K inhibitors, whereas the PTEN-loss-GS recapitulates IHC-detectable loss and could be more appropriate for use in studies of basal-like tumours, in which it is associated with high pathway activity [ 37].
Putin is implementing a "Fortress Russia" policy, which is based on repression at home and confrontation abroad.
As Prime Minister, he attempted to rule by creating a neo-conservative hegemony based on repression, racism, and a vitriolic anti-left stance.
As Prime Minister, he attempted to rule by creating a neo-conservative hegemony based on repression, racism and a vitriolic anti-left stance.
Characterization of these features could be easily followed by a novel technique based on differential repression of the green fluorescent protein expression (Chan et al., 2014).
The circadian clock of Arabidopsis, a popular model organism for plants, is more complex than expected, with negative feedback loops based on the repression of gene expression having a less exclusive role than previously thought.
For example, Kim et al. constructed a bistable switch based on cross-repression of promoter units by transcribed RNA molecules.
To elucidate the mechanism of multimeric assembly, we have devised two rapid and broadly applicable strategies for examining cooperative interactions between proteins bound to RNA, one based on cooperative translational repression of a two-site reporter and the other on gel shift analysis with crude E. coli extracts.
Our current mathematical model of the Arabidopsis clock includes repression of PRR9 by an evening gene and assigns this role to TOC1 based on the known repression of PRR9 expression in TOC1-overexpressing plants [ 19].
In contrast, we have focused on oligomerization in positive-feedback autoregulatory circuits, as well as genetic toggle switches based on the mutual repression of genes [ 15].
