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Candidate genes were prioritized based on reported phenotypes and natriuretic peptide receptor C (Npr3) was selected for sequencing based on the existence of seven known alleles (spontaneous and generated) with phenotypes similar to those of the Skm1 mice.
Based on reported phenotypes of neurog1 null mutant mice and other vertebrates, we strongly propose NEUROG1 as the causative gene in this boy.
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These constitute markers identified based on reported GWAS signals and candidate gene associations across pharmacogenomic and metabolic phenotypes.
Alleles that were tested were chosen based on previously reported neuronal phenotypes or the severity of the allele.
To extend this hypothesis based on the reported light-dependent phenotypes of elf3, McWatters et al. (2000) proposed that ELF3 fulfills the so-called zeitnehmer concept, in that this factor acts to bridge light perception to the clock.
Because of the fact that all *13 alleles encode the poor metabolizer as does CYP2D7, the corresponding phenotype is still accurately assigned based on the reported genotype.
Based on field reporting by Javier Marroquin and Amita Kulkarni.
These data suggest that the silencing efficiency based on the phenotype of T0 lines reported in Table 2 may be an underestimate.
Furthermore, Sahin et al. reported two groups of Xcv based on distinct disease phenotypes; these groupings were supported by a range of phenotypic and molecular assessments.
Based on recent reports, the surface phenotypes for non-HSCs and HSCs were defined in our study as CD45-lin-CD184+ and CD45+lin-CD184+ cells, respectively [ 5, 6].
Next, power analyses based on simulated phenotypes were conducted to analyze the influence of sample size, SNP density and causal variant location within the Poodle breed.
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