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Several studies on economic consequences of illness were based on reported or perceived illness [3], [4].
Sample size calculations of different interventions (n1 = n2, α = 0.05 and β = 0.1, two-tailed) were performed based on reported or pooled incidences.
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The 'Functional Use' data is either based on reported data or predicted by functional use QSAR models built on the harmonized functional use categories derived from reported uses [63].
For continuous outcomes, we calculated weighted standard mean difference based on reported means or medians.
The illnesses mentioned in this report are based on reported symptoms or names of illness reported by the respondents themselves.
In EQUIP, CONQUER and SEQUEL, based on reported AEs or the clinician-administered Columbia Suicide Severity Rating Scale questionnaire, the incidence of suicidality was not increased versus placebo and there were no suicidal behaviors [26,27,29].
Assignment to either group was based on reported evidence on the amyloid or non-amyloid nature of the deposits, as detected using electron microscopy and/or CR staining.
Poverty status was also determined at baseline and was based on reported annual household income below or above 125% of the 2004 US Department of Health and Human Services poverty guideline [ 23].
For NSHDS cases and controls, menopausal status at enrolment was determined retrospectively based on reported age at menopause on baseline or case control questionnaires.
For dichotomous outcomes, the number of patients experiencing an event was extracted or estimated based on reported percentages and ITT population.
It was then recoded into a binary variable, based on reporting one or more forms of deprivation (Yes/No).
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