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This is especially significant if we consider both the simplicity of the location assignment technique, and the relatively coarse grained nature of the data (based on relatively wide area bounding boxes).
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Furthermore, by sequencing and combining dozens of low-input methylomes from the same sample (e.g., one-cell, four-cell, or 20-cell pools), it will be possible to create composite methylomes that provide excellent genome-wide coverage based on relatively few cells and include an inherent assessment of variation.
Future studies should thus take into account the data source as well as test more drug-event associations, control for other confounders and increase sample size, especially since these estimates were based on relatively small numbers (as reflected in the wide CI).
But the United States has resisted an ASEAN-wide free trade area based on relatively weak rules acceptable to all ASEAN members.
In addition, the documentation for each outcome is based on relatively few events which in many cases lead to wide confidence intervals comprising the possibility of large benefit, no difference, and potential harm from the intervention.
(SLBMs achieve survivability by being based on relatively undetectable submarines).
Endeavor's apparent safety advantage, however, was based on relatively short-term data.
But most have been based on relatively small samples; this is the first study to compare national programs.
The sample is based on relatively strict inclusion criteria.
Furthermore, our study was based on a relatively wide range of exposure levels.
About two-thirds of its villages were situated on relatively wide hilltops while the remainder were built along slopes.
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