Sentence examples for based on reduced binding from inspiring English sources

The biochemical mechanism of the TFV resistance is based on reduced binding affinity and incorporation of TFV-DP.

The concept lies in the use of immunocytokines based on IFN mutants with strongly reduced binding affinity for the IFN receptor.

Here we demonstrate that inhibition of TNFR-1 on osteoblasts significantly reduced binding to S. aureus.

Therefore, based on our data that CUB4 and CUB5 mediate Sog interaction, we tested whether the molecular defect associated with these mutant Tld proteins is reduced binding to Sog.

Based on our findings, the (2S,3S) β-methylated analogues of our RGD sequences maintain their binding potency to the integrin receptors while the (2S,3R) β-methylated analogues exhibit a drastically reduced binding affinity.

Then, we calculated the percentage of binding based on 11438-peptide binding as 100%.

In addition, the electrostatic potential binding energy and similarity between the binding sites can be calculated based on the binding pose of the ligand.

which is based on tight binding method and is applicable only for the described slab.

The generation of the protomol was based on the binding site residue list previously defined.

However, previous studies identified the protein Scyl1 binding partner 1 (Scyl1basedbased on its binding to Scyl1 [30].

As shown, the results based on continuous binding scores outperform those based on discretized data.