Sentence examples for based on rat models from inspiring English sources
Pharmacokinetic and pharmacodynamic studies based on rat models suggested these newly constructed nanoassemblies with low cytotoxicity may function as novel nanoplatforms to efficiently and safely deliver therapeutics to achieve better efficacy but lower side effects.
An experiment based on rat model revealed that oral dose of 2000 mg EGCG/kg was lethal but dose with 200 mg EGCG/kg induced no toxicity [64].
An experiment based on rat model revealed that oral dose delivering 2000 mg EGCG preparation/kg was lethal to rats; but dose with 200 mg EGCG/kg induced no toxicity [ 81].
Experiment based on rat model showed that green tea extract with dose of 5% in diet for 13 wk induced thyroid enlargement in normal rats [ 88, 89] and other investigators studied the hepatotoxic effects of high dose EGCG, tea polyphenols, in male CF-1 mice and results indicated that higher bolus doses of EGCG are hepatotoxic to mice [ 90].
Our computational model of the rat left ventricle was based on experimental measurements of calcium, tension, left-ventricular pressure-volume (PV), and cardiac geometry.
The human anti-EC Kim-1 Mab binds to the same domain of rat's Kim-1, leading to a conclusion that experimental results based on rat's model could be seriously taken into concern for extrapolation to humans [ 26].
A human AZ1 model was generated from Swiss Model based on rat antizyme NMR structure (PDB code: 1ZO0), and fitted into the density.
We incorporated biological detail using sequential synaptic input onto spines in morphologically, electrically, and chemically detailed pyramidal neuronal models based on rat data.
The neurotrophic and neuroprotective properties of hNGF and hNGFR100E mutants were then compared in a neuronal amyloidogenic model [48] for neurodegeneration, based on rat hippocampal neuronal primary cultures.
Too much, and the patient bleeds out in the corner like a rat, because it's based on rat poison.
‡Primer designed based on rat HEV (GU345042).
