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Based on randomised comparisons by country and using the full length of follow-up of the different trials, DP recipients were at lower risk for a PCR confirmed failure compared to MAS3 in Thailand (P = 0.001), AL in Uganda (P = 0.004), and AQ+SP in Rwanda (P = 0.001)(figure 2, table S1).
These are observational by nature and are not based on randomised comparisons [ 12], thus the results should be interpreted with caution.
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Based on the study's result, the null-hypothesis that trends and performance differences inferred from naïve-indirect-indirect comparison based on evidence from clinical uncontrolled longitudinal studies and from direct comparisons based on randomised control trial (RCT) evidence, concerning conventional amalgam versus direct HVGIC restorations, have similar direction and magnitude, was rejected.
Although studies based on randomised trials have a valid comparison group, chance could explain the inconsistent findings because the sample sizes in all the studies were limited (<100 interval cancers).
Centralised 24 hour telephone randomisation based on randomised permuted blocks of 10.
At least with nudge theory, which is often based on randomised controlled trials, governments and NGOs can gauge the impact of new projects before they're scaled up.
Gong et al. [22] present a new collaborative filtering technique based on randomised perturbation and secure multiparty computation.
Ten studies (67%) were based on randomised clinical trials (RCTs) with time horizons ranging from 6 to 24 months.
Background and purpose: Concomitant chemoradiation (CRT) for locally advanced cervical cancer has become an established treatment based on randomised trials.
For example, in the health sector, systematic reviews of studies that are based on randomised trials are considered the most robust evidence.
i These data are based on randomised trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com