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No consensus exists about the number of sentinel lymph nodes (SLNs) that should be removed based on radioactivity counts in breast cancer, although the "10% rule" is often used.
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The second criterion was based on radioactivity; background counts (using either one 10-s count or the average of three 2-s counts), were measured directly on the patient ≥20 cm from the primary site and nodes were interrogated using a Neoprobe gamma detector before (in vivo) and after excision (ex vivo).
The ICP-MS data showed that with the exception of blood (where the mass of nanoparticles predicted from 99mTc radioactivity counts was only 20% lower than determined by ICP-MS) the actual gold content in all other major organs was 2 5 times higher than the organ uptake determined based on counts of radioactivity linked to the gold nanoparticle-stabilizing MPEG-gPLL1 layer.
One can identify the level of radioactivity at the tissue surface based on the measured counts in real time by moving the probe's head in the surgical field from tumour to adjacent normal background tissue of the same organ and back.
The sample radioactivity is estimated based on counting the photons emanating from the scintillation phenomenon in the crystal detector, but the number of counts often varies depending on the type of crystal detector and the counting software.
It is based on simple counting mechanism.
based on counting techniques.
The peristaltic pump is used to deliver prescribed volumes of [18F]fluoride solutions based on the decay-corrected radioactivity concentration and the desired amount of radioactivity.
Pharmacokinetic parameters were evaluated based on the total F radioactivity measurements in plasma followed by metabolite analysis using radio-HPLC.
The subsequent development of a plasmid based on luciferase activity instead of radioactivity resulted in stable transfection efficiencies [ 38].
The calculation of the amount of radioactivity was based on liver weight, conforming to the clinically used approach for TheraSphere®.
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