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We created screening and data collection tools based on published recommendations.
A list of these events, classified according to the body system and based on published recommendations 18 is shown in table 3. We have shown, in the first head-to-head randomised comparison of two TNF inhibitors for the treatment of RA in a study designed to reflect real clinical practice, that adalimumab is not inferior to etanercept in terms of persistence with therapy over 2 years.
The quality of each RCT related to a functional ingredient the efficacy of which was supported at least by one RCT was scored according to a standard set of 12 criteria based on published recommendations for the design of clinical trials in patients with OA [ 17- 20] (Table 2).
A case report form and instruction manual with clear definitions were created, based on published recommendations, including the ARRIVE guidelines.
Sedation was managed according to our medical ICU algorithm and based on published recommendations [ 5, 15].
The design of this economic evaluation alongside the CESAR trial is based on published recommendations [for example, [ 16]].
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An online questionnaire based on published guidelines and recommendations, conducted with seven clinical microbiologists, seven infectious disease physicians and five clinical pharmacists at nine Dutch hospitals.
A data collection form and instruction manual (see Additional files 1 and 2) were created based on published Canadian, US, and UK recommendations for reporting AR [28] [31].
Key recommendations based on published literature [1] [5], [8], [9] and expert opinions are given below to help review authors carry out indirect comparisons and to aid appropriate interpretation.
For recommendations based on published evidence, an appraisal about the generalizability to general practice was made.
The guidelines provide specific recommendations based on published data or derived from expert consensus.
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