Percentages of expected characteristics of all hospitalized patients based on published population rates [6] were compared to observed characteristics using the chi square statistic.
Estimates were based on published mutation rates for land snails.
All costs were converted to US dollars based on published exchange rates as of June 1 , 2009
Based on published mutation rates (Lang and Murray 2008; Lynch et al. 2008), we predicted zero to two mutations per WT genome and observed a slightly higher but comparable rate (median = 2.5 mutations/genome; range, two to four mutations).
Our estimates were based on published response rates associated with after-death interviews studies [ 2, 3], however, these teams were all able to contact family members directly and if contact could not be made, deemed ineligible.
Based on published literature, ypCR rate is less at 10 15% for rectal cancer patients treated with neoadjuvant CRT.
First, to estimate, based on published data, the acceptance rate of abstracts submitted to biomedical meetings.
Finally, based on published data, an incidence rate of 30 IPD cases per 100,000 individuals was used [ 24].
For adenovirus-, androvirusapovirus-related-related hospitalizations, estimates were generated for children <5 years of age, based on published pathogen-specific hospitalization rates (Supplementary Table S3).
